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When Tingle first meets Missy, he must bring her Ground Shell and Minced Meat. When he does this, Missy gives him a medicine that can be given to Tingle's bodyguard or the sick wife of the Port Town Guard.
Later, Missy is lost in Lon Lon Meadow, and cannot find her way home because she has lost her glasses. If Tingle finds her glasses for her, he is rewarded by her father, the Jeweler, for rescuing her.
For the rest of the game, Missy can be found in the eastern part of Port Town. If Tingle speaks with her after he has reached the Second Continent, she will tell him about a medic in the Gooey Swamp who has invented a new medicine, Tinglene. Once he has reached the Third Continent, she will tell him about the Shaman of Mount Desma who has invented another new medicine, Mega-Tingly.
|Tingle · Uncle Rupee · Pinkle · Barkle|
—Full list of characters
|Beetle Lord Death Bug · Captain Stalfos · Bana Bana · Beetle King Death Bug · Dora Dora · Uncle Rupee|
|First Continent · Second Continent · Third Continent · Rupeeland|
—Full list of locations
|Hero's Shrine · Pirate Hideaway · Deku Temple · Insect Cavern · Desma's Labyrinth|
|Bone Ocarina · Master Rupee · Mini Death Bug Chrysalis · Pure Dew · Rupee Goods · Super Rupees · Tingle Bomb · Tingle Tuner|
|Deity · Fairy · Human · Hylian · Salona · Yamatami|